Publications

SP Nutraceuticals Inc. was established in 2016 by Dr. Paul Spagnuolo and Christina Barbato.

 

 

October 30

Avocatin B Protects Against Lipotoxicity and Improves Insulin Sensitivity

The effects of an avocado‐derived fatty acid oxidation inhibitor, avocatin B (AvoB), on glucose and lipid metabolism in models of diet‐induced obesity and in vitro models of lipotoxicity are evaluated. 

Click here to read the full article.

March 25

Culinary Careers: The Food Scientist

Published March 25, 2019

Food science, a relatively new discipline compared to ancient ones such as farming, involves the application of biochemistry, microbiology and a slew of other scientific expertise to the food system. Some food scientists blend their knowledge with other disciplines to do potentially wondrous new things with food.

Read the full article here.

November 15
June 15

Relieving the pain of kidney stones

The power and promise of carbohydrate molecules.

Published June 16, 2018

For anyone who has suffered from kidney stones, the painful condition is not easily treatable, and patients are typically prescribed strong pain medication and fluids to alleviate symptoms. More stubborn stones can require surgery.

GlycoNet-funded research is testing the safety and efficacy of a glycoside, called arbutin, which is extracted from the bearberry plant. The molecule has shown a remarkable ability to break up kidney stones in pre-clinical studies.

Read the full article by the Canadian Glycomics Network here.

September 23
June 16

Avocados Provide Clue to Fighting Cancer

Published June 16, 2015

Avocados aren’t just Americans’ favourite fruit; they also may contain a key to fighting leukemia.

Molecules derived from avocados have been found to target the stem cells of acute myeloid leukemia (AML), according to a study published in the journal Cancer Research on Monday. The lipid found in avocado joins just a handful of drug treatments available that attack leukemia stem cells directly while leaving healthy cells unharmed.

Read the full article here.